@TransitBiker So, where in the sequence of #SarsCov2 did you or anybody else find #HIV sequences? How is that compared to other #SARS or # MERS #Corona viri? Any proper literature on anything? I call your hypothesis #bullshit.
Uli, #SarsCoV2 permanently kills off #TCells. With one or repeat infections, you can get #LongCovid as a result. By then, you are open to opportunistic infections.
Clean your indoor air with HEPA filters or a #CorsiRosenthalBox. Wear #N95 respirators or better. 😷
Boy, I just pick the most random times to watch mainstream media news. It’s been months but caught this as soon as I turned it on
🤔They’re shocked..
You know who isn’t shocked? None of us who have been following what #Covid does to #tcells
#KingCharles has been known for decades for being obsessed w/organic farming & he is epitome of privilege. But this #cancer Dx is not going to be connected with #saracov2 even though there’s a clear line
>90% of #TCR sequence diversity is generated by TdT-mediated nucleotide addition, but what is the benefit of TdT-altered TCRs? @MandlLab show that low-affinity #Tcells generated by TdT are important for curtailing chronic pathogen replication #PLOSBiologyhttps://plos.io/3HJKOCl
The great thing about high profile moron “experts” making blithe uninformed comments such as “Covid doesn’t really damage the immune system” is it angers people who ACTUALLY know & they come at them with #CovidPapers#Jha
This will be my continuing🧵on anything related to the destruction of #tcells#bcells#ImmuneDysregulation in an attempt to be organized if only for myself🖤
In truth just skimmed but my grasp on this in January 2024 is something that would have been impossible for me to understand in 2022 while experiencing my #sarscov2 2nd infection b/c my level of biology was zero & my lack of understanding led me to believe #hybridImmunity would give me 2 years at least. Mind you I never took my mask off except w/my MIL🦃🎄2021
Philip Dettmer “immune” book along w/the incredibly intelligent🧠🧠🧠here🐘&🐦have been invaluable in at least allowing me to read & generally follow along
Basically this study tells me, stay down for 6 months minimum
Surprisingly complex for a mainstream media article..
I don’t think it’s my imagination & surely others have noticed too that the further we go along since 2020, the #sarscov2#covid articles are getting less informative & for the most part useless in terms of information #EverythingIsNotFine
how about talking about how it damages #tcells instead of dated info from some immunology book back from when you were in Med school🙄
it👏🏼is👏🏼called👏🏼a👏🏼novel👏🏼virus👏🏼… for a reason!!!
also reasoning of not vaccinating #xbb for those under 65 to lessen burden on #nhs … 😶…😶😶😶😶😶🤯
Do these people hear themselves?🤦🏻♀️
I’m not dumb, ditzy on occasion but I get things eventually, however I read & see things constantly that are making me second guess myself; maddening
Prof Openshaw said: "The #viruses circulating now are pretty distant immunologically from the original #virus which was used to make the early #vaccines, or which last infected them.
"A lot of people have very little immunity to the #Omicron viruses and their #variants ."
WTF #misinformation is this?!?!
THERE IS NO NOR HAS THERE EVER BEEN DURABLE IMMUNITY TO A VIRUS THAT HAS MUTATED MORE IN 3 YEARS THAN FLU IN 15+++++ YEARS even if you were just infected
New publication! Kudos to the primary authors for their patience and stamina thru a long review process to get this over the finish line. Full TCR sequencing and lab analyses support CD8 T cells dominate vaccine responses in SARS-CoV-2 hybrid immunity. #COVID, #SARSCoV2, #TCELLS#hybridimmunity
Electric Pulses Induce Lung Cancer Immune Response
Results of a clinical trial show a lung cancer therapy using highly focused pulses with electrical energy show signs of immune responses that can treat the patients' tumors.
By the early 1990s, New York City was the epicenter of a nationwide tuberculosis epidemic. The city spent $1 billion to expand its TB control program, staffing the bureau with over 600 people to treat well over 3,000 cases a year.”
Last year there were 536 cases..
Now technically TB despite being #airborne should be kind of difficult to catch. My friend & his business partner got it from working in the same small office w/a🇬🇧intern who he also smoked pot with. However if your immune system is decimated by say having low #tcells you’re far more susceptible
Those #antibiotics were surreal looking; giant huge pink pills➕➕& you had to take them for a long time
A company with a process to generate new thymus tissue for immune system functions is receiving a $37 million award from the government's health breakthrough agency.
Important discovery linking the β-receptor, sympathetic nervous system, with T cell exhaustion, that has implications for LongCovid, POTS, post-viral syndromes & various cancers (by blocking β signaling) https://www.nature.com/articles/s41586-023-06568-6
Excellent Commentary & Post from Dr @erictopol .Fascinating discovery by @Annaglobig!
Exhausted CD8 #Tcells talk to sympathetic nerves in tissues & tumors. Tex cells express ADRB1 and localize near sympathetic nerves, listening to stress hormone noradrenaline. This promotes their dysfunction. @Tcellogic
PDF https://www.nature.com/articles/s41586-023-06568-6.pdf
'The question was – what was happening to the #TCells over 2 years in #LongCovid and recovered #COVID patients? Theoretically, the T-cells should have ramped up to knock down the virus, and once they did that, quieted down – but that’s not what happened at all – not even in the recovered group.
'Even in the recovered group, the T-cells remained abnormally activated in a whole slew of tissues – the brain stem, spinal cord, bone marrow, nasopharyngeal and hilar lymphoid tissue, cardiopulmonary vasculature, lung parenchyma, and gut wall. Finding so much remaining T-cell activation in the recovered patients suggested that the coronavirus infection had resulted in “a new immunologic steady state”.
'The T-cells could still be trying to cleanse the body of the coronavirus or they could reflect an autoimmune response. Whatever is happening it’s clear that infections – even infections that seem to have been fought off – have consequences.'
Results of a clinical trial show a vaccine delivered as a nasal spray protects healthy people against infection from the bacteria causing whooping cough infections.
Bad #COVID take by Dr. Ranney https://www.cnn.com/2023/08/28/health/risk-from-catching-covid-wellness/index.html
“At this point, the risk is lower because of our prior immunity, whether for severe outcomes or for long Covid,” said Dr. Megan Ranney, an emergency physician and dean of the Yale School of Public Health.
“Covid is still more dangerous than the flu, but its level of danger is becoming less,” she said, noting that we’re still very early in our human experience with the coronavirus, even four years in, and there are still things we don’t know.
A clinical trial assessing a synthetic antibody to generate an immediate response and also generate a more durable treatment for solid tumor cancers, advanced to a mid-stage study.
Results of a small clinical trial show genetically altered T-cells from patients with myasthenia gravis are well tolerated and reduce symptoms of the disease.
A clinical trial has begun testing a treatment for solid #tumor#cancers using engineered T-cells with proteins to attack specific tumor cells, but also avoid healthy cells.