auscandoc, to random
@auscandoc@med-mastodon.com avatar

Meanwhile in Albertastan

Alberta premier’s support for questioning worries experts | Globalnews.ca https://globalnews.ca/news/10511738/danielle-smith-covid-vaccine-town-hall/

“Blake Murdoch at the University of Alberta said framing the town hall as a chance to look at the international evidence of harm to children by COVID vaccines is a “reckless misrepresentation of what this event” is based on the guest list. (1/4)

auscandoc, to random
@auscandoc@med-mastodon.com avatar

Calgary #UCP hosting town hall on #COVIDvaccines https://calgary.citynews.ca/2024/05/14/calgary-ucp-vaccine-misinformation-town-hall/

“The claims made by these and the other four individuals set to speak have all been disproven and deemed false by medical professionals.

“many of the individuals that are participating in this event, that have been invited to speak have been discredited, have lost their license, and I know for them, they may hold it up as a badge of honour, but the reality is their perspective does not accord with what the science says,”

deewani, to random
@deewani@mastodon.social avatar

Via @erictopol Ground Truths episode: Akiko Iwasaki: The Immunology of Covid and the Future, A leading light in immmunobiology takes us through Long Covid, nasal vaccines, and the next frontier of the field https://erictopol.substack.com/p/akiko-iwasaki-the-immunology-of-covid.

deewani, (edited ) to random
@deewani@mastodon.social avatar

Are We FLiRTing With A New Covid Wave? A Covid Update via ERIC TOPOL@erictopol@mstdn.social

https://erictopol.substack.com/p/are-we-flirting-with-a-new-covid

deewani, to random
@deewani@mastodon.social avatar
deewani, to random
@deewani@mastodon.social avatar

Race for the next generation of Covid-19 vaccines
What’s in the pipeline? - Katelyn Jetelina
https://yourlocalepidemiologist.substack.com/p/race-for-the-next-generation-of-covid

DenisCOVIDinfoguy, to auscovid19
@DenisCOVIDinfoguy@aus.social avatar

The Centers for Disease Control and Prevention (CDC) finds no link between COVID vaccines and cardiac death in young people | forbes.com

@auscovid19

Source: https://www.forbes.com/sites/tylerroush/2024/04/11/cdc-finds-no-link-between-covid-vaccines-and-cardiac-death-in-young-people/?sh=402812ff577f

CDC study: https://www.cdc.gov/mmwr/volumes/73/wr/mm7314a5.htm

auscandoc, to random
@auscandoc@med-mastodon.com avatar

cut risk of virus-related and blood , study finds | Medical research | The Guardian https://www.theguardian.com/science/2024/mar/12/covid-vaccines-cut-risk-virus-related-heart-failure-blood-clots-study “Covid vaccinations substantially reduce the risk of heart failure and potentially dangerous blood clots linked to the infection for up to a year, according to a large study. (1/2)

DenisCOVIDinfoguy, to auscovid19
@DenisCOVIDinfoguy@aus.social avatar

COVID vaccines cut risk of virus-related heart failure and blood clots, study finds

Researchers analysed health records from more than 20 million people across the UK, Spain and Estonia and found consistent evidence that the jabs protected against serious cardiovascular complications of the disease

The latest study sought to investigate the overall impact of a Covid vaccination, given that infection with the virus itself is known to significantly raise the risk of heart failure and various other serious cardiovascular problems.

Source: https://www.theguardian.com/science/2024/mar/12/covid-vaccines-cut-risk-virus-related-heart-failure-blood-clots-study

Study: https://heart.bmj.com/content/early/2024/01/24/heartjnl-2023-323483

@auscovid19

deewani, to random
@deewani@mastodon.social avatar
deewani, to random
@deewani@mastodon.social avatar
DenisCOVIDinfoguy, to auscovid19
@DenisCOVIDinfoguy@aus.social avatar

Do the latest vaccines better protect us from COVID-19? By Angus Dalton

Research hasn’t been peer reviewed yet: https://medrxiv.org/content/10.1101/2024.02.08.24302032v1

Source: https://smh.com.au/national/do-the-latest-vaccines-better-protect-us-from-covid-19-20240213-p5f4oj.html

@auscovid19

This is the first analysis in the world to try to answer that question. The results are fascinating, but there are important caveats – chief among them that the research is a pre-print, so it hasn’t been peer reviewed yet. Let’s take a look. The vaccine-variant arms race By the time a new COVID vaccine is tested, approved and released, invariably the immunogen used to create the vaccine – i.e. the spike protein it’s designed to replicate in the body – doesn’t match up with the dominant variant circulating in the community. “Things move on, the virus mutates very quickly,” says Associate Professor Deborah Cromer, lead author of the research and head of the Infection Epidemiology and Policy Analytics Group at the Kirby Institute at the University of NSW. The XBB1.5 monovalent vaccine is the newest booster available in Australia. But XBB1.5 – the “Kraken” variant – reached the height of its power about a year ago. JN.1 is the variant now dominant in Australia, the US, France and India. Taking a look at the variant distribution in NSW, you can see XBB1.5 occupies a tiny share of COVID-19 infections, whereas JN.1 is responsible for about three-quarters of infections.
If the rise of new variants continually outpaces new boosters, is there a benefit to updating the vaccines at all? As Cromer says: “We want to balance the cost of updating a new vaccine – and what we’d have to pay vaccine manufacturers – with the potential benefit that’s going to be gained from it.” Increasing protection To pin down that benefit, Cromer and her colleagues drew on studies that compared the neutralisation titre – that is, the level of vaccine-busting antibodies in people’s blood – produced by different vaccines. “Once we accounted for all the obvious differences between the groups, there was still essentially a 40 per cent higher boost to neutralising antibody titres for every vaccine update,” Cromer says. That’s a 40 per cent greater antibody response from each new vaccine. And that improvement applies across different COVID strains we’re exposed to – not just the specific variant a person has been immunised against. However, a 40 per cent increase in neutralisation titre doesn’t automatically translate into 40 per cent better protection against symptomatic and severe disease. In previous data analyses, Cromer and her colleagues established a quantitative relationship between the level of neutralising antibodies in the blood and protection from COVID. They drew on this relationship to predict the effect that a 40 per cent increase in antibodies would have on clinical outcomes.
For Associate Professor Paul Griffin, an infectious disease expert at the University of Queensland who wasn’t involved in the study, the findings underscore the benefits of faster vaccine rollout. “Forty per cent is a useful improvement,” Griffin says. “But it’s likely the improvement could’ve been greater if there weren’t delays in rolling out those vaccines.” He said a quicker regulatory process, the capacity to manufacture RNA vaccines in Australia, and better-designed vaccines that include multiple variants, would improve future boosters’ ability to protect people. Chair of epidemiology at Deakin University, Professor Catherine Bennett, points out the study’s 40 per cent finding has a wide confidence interval – statistical guardrails around the final estimate. While 40 per cent is the researchers’ best guess, the actual improvement between each vaccine could be as low as seven per cent or as high as 82 per cent. “It might be an even stronger effect, or it might be a lesser effect – there isn’t the precision in this study to show it,” she says. “But what it is showing is … that you do get this better neutralising response with the more recent vaccines.” While the pattern of strengthening vaccine effectiveness is welcome, we don’t know exactly why it’s reliably increased, given the mismatch between vaccines and variants. And the pattern may not last forever.

indianewswatch, to india
@indianewswatch@kolektiva.social avatar

“Doing bioethics” in an era of nationalism: The Vaccine War

Indian cinema seems to have moved away from incorrect depictions to blatant falsehoods. The Vaccine War is a shining example. Rohin Bhatt writes.

https://ijme.in/articles/doing-bioethics-in-an-era-of-nationalism-the-vaccine-war/?galley=html

DenisCOVIDinfoguy, to Europe
@DenisCOVIDinfoguy@aus.social avatar

COVID vaccines saved at least 1.4 million lives in Europe, WHO says

🔹COVID-19 vaccines reduced deaths by 57% between December 2020 when the vaccine rollouts began and March 2023, the study found.

@WHO @auscovid19

Source: https://www.euronews.com/next/2024/01/16/covid-vaccines-saved-at-least-14-million-lives-in-europe-who-says

erictopol, to random
@erictopol@mstdn.social avatar

An exciting development for a new Covid vaccine: inhaled single dose induces strong mucosal immunity and protection in multiple species, including non-human primates, and prevents transmission across all variants assessed

https://nature.com/articles/s41586-023-06809-8

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deewani,
@deewani@mastodon.social avatar
DenisCOVIDinfoguy, to auscovid19
@DenisCOVIDinfoguy@aus.social avatar

🇦🇺 Australia: "Two Melbourne-made COVID vaccines are now ready for commercial partnerships to help bring them to market, with hope that one can be delivered as a nasal spray."

@auscovid19

Source: https://www.heraldsun.com.au/lifestyle/health/a-spray-for-next-generation-of-covid-vaccines/news-story/51137731d54fa57cd2416bfc05040311

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deewani, to random
@deewani@mastodon.social avatar

REMINDER : Free Covid vaccines for under- and uninsured via CDC’s Bridge Access Program only covered thru 12/31/24. If you know anyone in this category, please let them know. https://www.cdc.gov/vaccines/programs/bridge/index.html

DenisCOVIDinfoguy, to australia
@DenisCOVIDinfoguy@aus.social avatar

🇦🇺 Australia: Millions of Aussies ruled ineligible for improved COVID vaccines.

"The Federal Government has secured about 3 million doses of the XBB.1.5 vaccines. That is 1.2 million fewer than the number of Australians aged 65 and over."

@Mark_Butler_MP @auscovid19

Source: https://thewest.com.au/news/coronavirus/millions-of-aussies-ruled-ineligible-for-improved-covid-vaccines-c-12628587

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JaneDoeTheFirst, to random
@JaneDoeTheFirst@zeroes.ca avatar

PSA re: Novavax

I talked to my immunologist/allergist this morning as I have to go through a 2 week course of treatment before getting my Pfizer shot. I've been unlucky in that even though it helps it doesn't completely remove the (non-life-threatening) adverse effects.

I had hope for Novavax here in Canada. My allergist (ditto my pharmacist) said it wasn't available(Ontario), and that he wouldn't recommend it anyway. He said that both the new adapted Pfizer and Moderna are far more effective. I am so bummed. 💦

I suppose we should take any information with a grain of salt these days even from experts but information remains scarce. I just thought I'd let people know. I'm biting the bullet and going ahead.

Thanks to all the uncaring clods out there who continue to contribute to my bit of misery.

And a giant heartfelt thank you to all those here who are so supportive (especially zeroes.ca) and keep me going and alive.💖

@novid

deewani, to random
@deewani@mastodon.social avatar

PSA Novavax is not stored frozen.

Visited local CVS inside a Target to ask how to schedule an appointment for Novavax. I was able to get a walk-in vaccination, their very first Novavax administered. At first I became alarmed when she said it had to thaw. I worried and asked if it was being stored frozen. She then recalled it was not frozen and showed the refrigerator with clear door where it was stored.
2X Pfizer 3X Moderna 1X Novavax.

deewani, to random
@deewani@mastodon.social avatar

https://www.vaccines.gov/ is showing Novavax at CVS & Costco locations in the San Francisco Bay Area. However CVS website does not have Novavax as a choice when booking appointment online. Free vaccines for under- and uninsured via CDC’s Bridge Access Program only covered thru 12/31/24.

deewani,
@deewani@mastodon.social avatar

“October 13, 2023
Novavax's updated COVID-19 vaccine is now available at a wide range of retailers, including Costco, CVS Pharmacy, Giant, Publix, Rite Aid and Stop & Shop
Novavax's vaccine is the only protein-based non-mRNA COVID-19 vaccine option in the U.S.
Novavax's vaccine finder is available at us.novavaxcovidvaccine.com” https://ir.novavax.com/press-releases/2023-10-13-Novavax-COVID-19-Vaccine-Doses-Available-at-Major-Retail-Pharmacies-Across-the-U-S

herhandsmyhands, to random
@herhandsmyhands@romancelandia.club avatar

PSA: if you cannot receive an MRNA Covid Vaccine, you can now make an appointment at COSTCO to get the newly approved Novavax for COVID-19; use the link, or call to check if they take walk-ins.

Remember: you don't have to wait six months to get it.

Go forth and be safe.

ETA: screenshot of FDA fact sheet

https://costco.web.medrefill.com/csweb/#/store

Ruth_Mottram, to random
@Ruth_Mottram@fediscience.org avatar

PSA:

Its Danish + vaccination season again. Last year the entire family got flu except me, and it ruined our Christmas. I had the jab and .

Here is the Danish page on who, how and where to get your and this year.

https://www.sst.dk/da/vaccination

CaroltheCrone, to random
@CaroltheCrone@mastodon.sdf.org avatar

Covid levels in my zip code are at almost half that of their highest rate during omicron.

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