H5N1, the avian flu

Infoseepage,
@Infoseepage@mastodon.social avatar

Another dairy worker, this one in Michigan, has tested positive for H5N1 after showing signs of illness. Like the two others, this person had eye symptoms. Unlike the others, this person had a productive cough. If it is infecting human respiratory tissues, that isn't good, as coughing makes someone far more likely to spread the disease onward.

https://www.statnews.com/2024/05/30/bird-flu-third-case-human-infection-caused-respiratory-symptoms/?utm_campaign=breaking_news&utm_medium=email

SylvainLagu, French
@SylvainLagu@mastodon.social avatar

🇨🇦

Canadian scientists launch early warning system to spot traces of H5N1 bird flu in milk

https://www.cbc.ca/news/health/h5n1-bird-flu-early-warning-system-1.7218486

cbarbermd,
@cbarbermd@med-mastodon.com avatar

Nationally, #H5N1 has been found in 4 🦙 alpacas in Idaho, 2 dead feral 🐈 cats in New Mexico and 67 dairy 🐄 herds across nine states. With more animal to animal transmission, two recent human cases in the U.S. and a potential mortality rate of 50%, we need to ramp up surveillance efforts…

#usda #worldhealthorganization #CDC #outbreak #press
https://www.cidrap.umn.edu/avian-influenza-bird-flu/alpacas-infected-h5n1-avian-flu-idaho

kakape,
@kakape@mas.to avatar

Add another name to the list of mammal species infected with : alpacas.
It’s not surprising at this point but it certainly isn’t reassuring either that this virus just keeps spreading farther and wider…

https://www.aphis.usda.gov/livestock-poultry-disease/avian/avian-influenza/hpai-detections/mammals/highly-pathogenic-avian

KeithDJohnson,
@KeithDJohnson@sfba.social avatar

"Researchers at the University of Wisconsin-Madison squirted raw H5N1-containing milk from infected cows into the throats of anesthetized laboratory mice, finding that the virus caused systemic infections after the mice were observed swallowing the dose. The illnesses began quickly, with symptoms of lethargy & ruffled fur starting on day 1. On day 4, the animals were euthanized to prevent extended suffering. Subsequent analysis found that the mice had high levels of H5N1 bird flu virus in their respiratory tracts, as well their hearts, kidneys, spleens, livers, mammary glands, and brains.

"Collectively, our data indicate that [Highly Pathogenic Avian Influenza] A(H5N1) virus in untreated milk can infect susceptible animals that consume it," the researchers concluded. The researchers also found that raw milk containing can remain infectious for weeks when stored at refrigerator temperatures."https://arstechnica.com/science/2024/05/after-mice-drink-raw-h5n1-milk-bird-flu-virus-riddles-their-organs/

harold,
@harold@mastodon.social avatar

«"I had lots of people say, 'Who cares about the mammary glands? Why do you care about what happens if an influenza virus infects a breast?'" recalled the virologist [Dr. Alyson Kelvin].

"Well, I have a long list of reasons. But it was really hard to get more funding to understand the answers to those questions."»

https://www.cbc.ca/news/health/bird-flu-in-u-s-cows-caught-scientists-by-surprise-canadian-research-has-seen-it-coming-since-1953-1.7212587

#H5N1 #PublicHealth #pandemic

rchusid,
@rchusid@med-mastodon.com avatar
JohnJBurnsIII,
@JohnJBurnsIII@kzoo.to avatar

@rchusid

I don't want to be in the same room as these people!

I don't want to get that flu because they are stupid.

☹️ 🤬

kegill,
@kegill@mastodon.social avatar

“raw milk containing can remain infectious for weeks when stored at refrigerator temperatures”

Common sense substantiated by research, that.

Researchers also gave mice raw milk containing H5N1. The virus almost immediately began affecting them.

Euthanized on day four, and still:
“the mice had high levels of H5N1 bird flu virus in their respiratory tracts, as well their hearts, kidneys, spleens, livers, mammary glands, and brains.”


https://arstechnica.com/science/2024/05/after-mice-drink-raw-h5n1-milk-bird-flu-virus-riddles-their-organs/

veganpizza69,
@veganpizza69@veganism.social avatar

"New tests confirm milk from flu-infected cows can make other animals sick — and raise questions about flash pasteurization"

More research:

<💬>
First, they confirmed the raw milk was chock-full of H5N1 virus. Then, they stored some of the raw milk at refrigerator temperature to see if levels of the virus in milk would drop off over time. Over 5 weeks, viral levels in raw milk dropped a bit, but not much.
</💬>

This should also imply that the virus gets into fermented raw milk products. And if you look for "raw milk ice cream", you'll see that there are sellers and there is a market. I find the issue of ice cream more interesting because it can be stored for a long time, which means outbreaks later.

<💬>
Heating the milk to 72 degrees Celsius, or 181 degrees Fahrenheit, for 15 or 20 seconds — conditions that approximated flash pasteurization — greatly reduced levels of the virus in the milk, but it didn’t inactivate it completely.
</💬>

This is flash pasteurization, meaning that the heat is applied for a shorter duration, but at a higher temperature. And this is the most common method; I've seen it in action and it's usually some nice machine that efficiently does this, which means that it's cheaper than the "vat pasteurization". Speaking of vat, I'm not sure how many people still do this since the rise of "cartons", but I grew up with raw milk plastic bags and boiling the milk; unfortunately, I wasn't raised vegan. Anyway, I distinctly remember the challenges of boiling cow milk, so I wonder how many of the raw milk buyers are doing their own pasteurization (boiling = vat pasteurization at high temperature).

<💬>
“But, we emphasize that the conditions used in our laboratory study are not identical to the large-scale industrial treatment of raw milk,” senior study author Dr. Yoshihiro Kawaoka, a virologist who specializes in the study of flu and Ebola, said in an email.
</💬>

It's true that further processing, which is done in these milk factories, can change the results. They mention the importance of homogenization, but there's also dilution as cow milk is pooled from many sources, so if just a small % of that is infectious, then the dilution will reduce the viral load per unit of fluid, making pasteurization more likely to succeed. I'm not sure about the homogenization and emulsification help in this sense:

<💬>
a process that emulsifies the fat globules in milk so the cream won’t separate.
</💬>

I'm not sure about this one. I've seen this in research on tuberculosis bacteria in milk, but not for viruses. Just like with SARS-CoV-2, there is a question of the non-linear effects of viral load (more viral particles, exponentially worse outcomes). They can't really answer. And, who knows, maybe homogenization will make it easier to cow milk to be accidentally aerosolized and/or inhaled.

I wouldn't CNN to go for the pessimistic reporting...

So, yeah. The raw cow milk drinkers are working stochastically to bring about a new pandemic. And probably new waves of as a bonus tuberculosis. Did you know about drug resistant tuberculosis? https://en.wikipedia.org/wiki/Multidrug-resistant_tuberculosis

https://edition.cnn.com/2024/05/24/health/new-experiments-milk-h5n1-infected-cows-raise-questions-flash-pasteurization/index.html

dancingdogs,
@dancingdogs@forall.social avatar

Researchers at the University of Wisconsin-Madison squirted raw H5N1-containing milk from infected cows into the throats of anesthetized laboratory mice, finding that the virus caused systemic infections after the mice were observed swallowing the dose. The illnesses began quickly, with symptoms of lethargy and ruffled fur starting on day 1. On day 4, the animals were euthanized to prevent extended suffering.

https://arstechnica.com/science/2024/05/after-mice-drink-raw-h5n1-milk-bird-flu-virus-riddles-their-organs/

nitpicking,
@nitpicking@mstdn.party avatar

@dancingdogs Mice seem to much more susceptible to H5N1 strains adapted to birds than humans are. I am not suggesting raw milk is a good idea, because it objectively is not. For one thing, I don't really want to catch or spread tuberculosis, either.

8petros, Polish

Jak to jest z tą "ptasia" grypą #H5N1, ktoś podpowie? Czy ona się na inne zwierzęta przenosi tylko drogą pokarmową? Akurat się przymierzam do produkcji jogurtu, i nie wiem, czy wystarczy wyselekcjonowany dostawca, czy od razu zrezygnować z krowiego?

justyourluck,
@justyourluck@masto.ai avatar

Clarification from the USDA re:

"...interstate movement for a lactating dairy cow from a sale barn directly to a slaughter facility requires only a Certificate of Veterinary Inspection (CVI) stating that the animal is clinically healthy; no testing is necessary."

I'll repeat that in case you missed it.

NO TESTING IS NECESSARY for dairy cows being sent to slaughter.

I suspect "clinically healthy" is a bit misleading in a similar way that "mild " is

https://www.aphis.usda.gov/livestock-poultry-disease/avian/avian-influenza/hpai-detections/livestock

grumpybozo,
@grumpybozo@toad.social avatar

@justyourluck Also: cows from dairy operations are mostly not slaughtered for human consumption. So this meat is going into stuff like dog food. Where it can encounter yet another mammal, if it somehow escapes thermal destruction.

justyourluck,
@justyourluck@masto.ai avatar

@grumpybozo

As far as pet food goes, there has been ZERO warnings to consumers of raw pet food with regards to H5N1 so if that's where it's going, this needs to be addressed in a big way.

https://mastodon.social/@carstenfranke

arisummerland,
@arisummerland@beige.party avatar

Y'all will find this... interesting.

I was helping a farmer friend today get her car up to her mechanic's place, which is about 10 miles out of town.

On the drive back, she took a call from someone who was looking for raw cow's milk.

She's only on Facebook as far as social media goes, so she hasn't seen any of the news stories about people seeking out raw milk in order to try to infect themselves with to "gain immunity" from it.

She was gobsmacked!

I was trying SO hard not to laugh while she took the call.

I told her that I've seen a number of news stories about people doing exactly this. I said what scares me the most is, the mortality rate is over 50%. One in two people! Why would anyone think this is an acceptable risk?

She appreciated the information I gave her and said that she would adjust her response when she received more calls.

Apparently she's received a lot of calls recently.

She's not even a dairy farmer!

I know 100+ years ago when we didn't have , , or , exposing yourself to pathogens was one way to possibly gain immunity from whatever was going around.

But thousands upon thousands of people were sickened and died from things that we can now prevent or treat with drugs, , , , and vaccines. It wasn't all bread and roses in pre-modern America. Our average life expectancy was almost half what if is today.

"Natural" is not inherently superior. Immunity debt is fucking bullshit. Exposing yourself willingly to a deadly pathogen does not increase your chances of living longer or being healthier afterwards. If someone did this to their kids? It would be flat out child abuse.

Yet, I always forget that most of the population doesn't read a book after they leave school, doesn't believe in science, and thinks if something is on the internet, it must be true.

Even and especially, people in my profession and allied professions believe the wackiest ideas about how the the human body works that are simply not true.

I'm pretty tired of the stupidity of other humans at this point. Go ahead. Drink the raw milk. Take yourself out of the gene pool. I know I can't do anything about it once you've made up your mind to do something so risky and stupid. SMH

arisummerland,
@arisummerland@beige.party avatar

@mentallyalex This absolutely is what's going to happen. This kind of idol worship and health supremacism is rampant in the natural health and wellness community. 🙄

mentallyalex,
@mentallyalex@beige.party avatar

@arisummerland :ablobcatnod:

Coupled with the macho-isms and "winner/loser" mentalities and we have a fun recipe for a bunch of survivors bias.

Infoseepage,
@Infoseepage@mastodon.social avatar

We've currently got 2 confirmed dairy worker H5N1/HPAI infections in 2 months from 52 confirmed infected dairy herds. There were 27,932 dairy herds in the US as of 2002. Back of the napkin math tells me that if all those herds became infected, one would expect dairy workers to become infected at a rate of around 537 workers a month, but we're of course taking stringent measures to ensure more dairy herds don't get infected right? Right? Right?

ai6yr,
@ai6yr@m.ai6yr.org avatar

NYTimes: "A Second Dairy Worker Has Contracted Bird Flu, C.D.C. Reports

The new case, in a Michigan farmworker, did not suggest that bird flu was widespread in people, health officials said, adding that the risk to the general public remained low." https://www.nytimes.com/2024/05/22/health/h5n1-bird-flu-dairy.html

Forbearance,
@Forbearance@mastodon.xyz avatar

@ai6yr so happy to hear from the Center for Disease Commentary

ai6yr,
@ai6yr@m.ai6yr.org avatar

@Forbearance 😂 on the new acronym. (to be fair, I think they have wanted to do good, but have been so warped by politics they have lost the trust of the public).

curt_nordgaard,
@curt_nordgaard@mstdn.social avatar

Just to clarify a technicality from some of today’s headlines:
There was actually a <third> person diagnosed with highly pathogenic avian influenza today according to the CDC dashboard. It was the <second> among dairy workers (both of whom had conjunctivitis, whereas the case of an infected poultry worker presented with fatigue).

haeji,
@haeji@mastodon.online avatar

So second human case of H5N1 was NOT detected with nasal swab, but EYE swab. Sounds like if you have pink eye, go get tested from the eye for potential . I have to ask, how many of the 40 human tests were done with eye swab?
"A nasal swab from the Michigan worker tested negative for influenza in the state, but an eye swab from the patient was shipped to CDC and tested positive for the H5N1 virus, the CDC said."
https://www.reuters.com/world/us/second-human-case-bird-flu-linked-dairy-cows-detected-us-stat-news-reports-2024-05-22/

kakape,
@kakape@mas.to avatar

Michigan just reported a human case of in a dairy worker, the second human case linked to the ongoing outbreak in dairy cows in the US.
As in the previous case in Texas, the worker only reported eye symptoms.

justyourluck,
@justyourluck@masto.ai avatar

Huh. This is rather refreshing.

"We say we don’t believe that there are cases of H5 novel influenza circulating because we haven’t seen any evidence that would be suggestive of that. But until and unless we enhance our subtyping...

👉 we are basing that conclusion on negative implication rather than on affirmative data,” Shah said in the interview.

https://www.statnews.com/2024/05/21/h5n1-bird-flu-cdc-urges-summer-flu-surveillance/

CaroltheCrone,
@CaroltheCrone@mastodon.sdf.org avatar

When H5N1 goes off the rails as it almost certainly will in the not-too-distant future, who do you want to be in charge of the country?

Competent leaders and scientists or a clown show. Because this stuff is not a joke.

A new unreviewed preprint is ringing alarm bells about the possibility of human to human transmission coming from cows. (Similar to the problem with pigs.) It's not good.

https://www.statnews.com/2024/05/21/h5n1-bird-flu-cdc-urges-summer-flu-surveillance/

KeithDJohnson,
@KeithDJohnson@sfba.social avatar

"Researchers who sequenced viruses from wastewater samples from 10 Texas cities found virus in 9 of them, sometimes at levels that rivaled seasonal ."
https://www.cidrap.umn.edu/avian-influenza-bird-flu/wastewater-testing-finds-h5n1-avian-flu-9-texas-cities

Wen,
@Wen@mastodon.scot avatar

@KeithDJohnson @ColesStreetPothole it doesn’t matter in Texas their politicians have ruled infections non existent to help with a potential outbreak of vaccinations.

KimPerales,
@KimPerales@toad.social avatar

We're thankful for scientists who are working to keep Americans safe from , that's currently infecting dairy cattle:

"Move over, wastewater. Store-bought milk could be another way to track the bird flu outbreak in cows.

Scientists have managed to generate a full genetic sequence of from store-bought milk, suggesting commercial milk products could be a way to monitor the outbreak in cows, given the lack of cooperation from dairy farmers.

https://www.statnews.com/2024/05/21/bird-flu-virus-spread-scientists-monitor-h5n1-in-store-bought-milk/

ai6yr,
@ai6yr@m.ai6yr.org avatar

FluTrackers reports three domestic cats diagnosed with H5N1, not associated with poultry or dairy cattle HPAI. https://flutrackers.com/forum/forum/united-states/h5n1-tracking-af/south-dakota/988632-south-dakota-avian-flu-in-mammals-2024#post990807

Nonya_Bidniss,
@Nonya_Bidniss@mas.to avatar

"Is the virus in milk infectious?"
"From...if it's coming out of a cow, yeah. Absolutely. ... The virus loves it inside that udder."

Again, don't drink raw milk, dummies! Even without influenza, there's all kinds of stuff in there that's killed off by pasteurization.

Dr. Richard Webby joined for the recent episode on in cows. Website: https://www.microbe.tv/twiv/twiv-1113/
YouTube: https://www.youtube.com/watch?v=uPI9Fte5s3k

chargrille,
@chargrille@progressives.social avatar

Who is tracking closely?

Somewhat closely?

Who should I be following?

I have questions about the quality of research identifying temperature at which the virus is guaranteed to be killed.

Other questions too. Always with the questions.

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