@trendless@zeroes.ca
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trendless

@trendless@zeroes.ca

Following those who have experience w/ chronic illness, those who are keeping up with the literature, and those sacrificing to keep us all safe; wearing P100 respiratory PPE, pursuing personal zero SARS-CoV-2

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"COVID is back" only in the sense that media+govts are talking about it again. It never went away.

Just because you hadn't been hearing the word doesn't mean it wasn't being spoken about, knowingly or otherwise.

While the aforementioned entities don't suffer symptoms or illnesses that necessitate explanation, they do discuss delays, worker shortages, supply chain disruption, etc.

On the other hand, an individual must use euphemisms like allergies, summer cold, under the weather, out sick, fatigue, brain fog, diabetes, autoimmune disease, cancer, natural causes, etc, to gloss over new or ongoing health issues.

trendless, to novid
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“It’s time for our society to admit that we’ve made a mistake and change course.”

> Prioritizing the economy over health will sink both
https://calgaryherald.com/opinion/columnists/opinion-this-is-a-pandemic-of-attrition

@novid

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When authorities decided to downplay the most contagious pathogen ever and the most severe pandemic threat in a hundred years, it was inevitable that they'd have to take that same position on all future pathogens and pandemic threats. Humanity is suffering for taking an absolutely irresponsible position and not being able to climb down from it. We will continue to suffer until we do.

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When using COVID RAT/LFT:

Wait thirty (30) minutes after eating, drinking, brushing teeth, chewing gum, smoking, vaping, using nasal/throat spray, etc, before performing test.

Swab cheek, throat, & nasal cavity.

Nasal cavity is straight back, not up the nose.

Positive tests are accurate, negative are not; test at least three (3) times, at forty-eight (48) hour intervals. Also be aware that a strain is known to be circulating in India that evades detection for up to seven (7) days after symptom onset.

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Desperate to hold onto their ever-shrinking workforce, but still unwilling to walk back their ignorance and lose face, Dell management thinks, “hey, let's screw our healthiest, most productive employees using whatever leverage we have left,” is the way?

> Dell Workers Can Stay Remote - But They're Not Going to Get Promoted https://ca.movies.yahoo.com/movies/dell-workers-stay-remote-mdash-110401493.html

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Client: "Will you mask for me?"

Service Provider: "I'm not required to."

What hath public health wrought?

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Say it with me:

"SARS-CoV-2 is not the flu"

I know there's at least one person who still needs to hear this today.

trendless, (edited ) to novid
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There's one layer of swiss cheese that I would never omit:

Respirators.

This is the only layer that can prevent close-proximity transmission.

As long as you're wearing one that you know seals to your face and isn't soaked or super old, it's going to protect you from all the invisible ways #TrojanAir can get into your nose and mouth.

And even if you haven't proven that it seals, it's damp, or you've worn it a bunch of times before, it's still going to provide more protection than any other layer(s).

Please, please don't think you can compensate for being unmasked by utilizing combinations of other layers.

All the other layers are designed to make a respirator more effective or provide backup in the event a respirator lets a bit of something through. Even vaccines were trialled in the context of universal masking; their original efficacy numbers are a product of that environment.

#MakeYourMaskWorkBetter

If you can't get your hands on any respirators, reach out and I'll connect you to someone in your region who can help. If I have to ship you some myself, I will.

#MaskUp #WearARespirator #N95 #FFR #P100 #Elastomeric

@novid

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Regarding coronaviruses, circa 2017

But sure, tell me again how we'll eventually develop herd immunity?

> Why Don’t We Ever Develop Immunity Against the Common Cold? https://www.technologynetworks.com/immunology/news/why-dont-we-ever-develop-immunity-against-the-common-cold-294551

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Wait until the virus enters your body to fight it :GeordiSaysNo:

Keep the virus from entering your body :GeordiSaysYes:

:aura: :vflex: :xplore1900: :n95:

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This is the kind of bureaucratic garbage that caused -- and is still causing -- the pandemic. Good on Cal/OSHA for at least trying to employ science.

> CDC rift with Cal/OSHA over when to use N95 masks could put California health workers at risk again https://www.sfchronicle.com/health/article/n95-mask-cdc-covid-18540474.php

@novid

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trendless, (edited ) to novid
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>SARS-CoV-2 is a protean virus. It seems designed to reinfect a previously infected host, changing its outer coat as well as some of its properties.

>We all remember Omicron and how it swept the world that had already experienced several waves of Covid cases. There were so many changes in the outer spike protein of Omicron that previous infections did little to protect from new infections. How much previous infection protects from disease still remains in question.

>BA.2… contained 54 amino acid mutations from the original Wuhan virus. The cause for concern with BA.2.86 is that it contains 41 amino acid mutations on top of the BA.2 mutations, totaling 95 mutations from the Wuhan virus.

>BA.2.86 is likely a common descendant of one of the original Omicron variants, BA.2, [?and a more recent variant, XBB?]. In the spike protein of BA.2.86, we see 60 amino acid mutations, including substitutions and deletions. For context, the Alpha variant, which fueled the second-largest surge of cases in the United States behind the initial Omicron surge, contained just ten spike amino acid mutations. Dr. Eric Topol describes BA.2.86 as "Omicron Squared."

>…the updated Covid vaccine set to be released this fall is designed to protect against the XBB.1.5 variant, but not BA.2.86. The hope is that the vaccine will protect against BA.2.86 should it widely circulate, but it would be unsurprising if the variant evaded booster protection, given the degree to which BA.2.86 is mutated in the spike is extreme.

https://www.forbes.com/sites/williamhaseltine/2023/08/24/covid-19-the-shapeshifting-protean-virus/

@novid

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> Alberta Medical Association sounding alarm, calling for more support as hospitals are overwhelmed
https://calgary.citynews.ca/2023/12/11/alberta-medical-association-support-hospitals-overwhelmed/

The alleged problem:
“...there is a confluence of factors that are driving physicians out of hospitals, and this is negatively affecting Albertans’ access to timely, acute care.”

The proposed solution:
“Match alternative relationship plan rates to current fee-for-service billing in Alberta; Incent after-hours care; Provide competitive rates for physician availability; Address and remove further compensation reductions.”

• How long have we been sounding the alarm that this was the inevitable outcome of LetErRip™?

• Is there so much denial even among physicians/hospitalists in Alberta that they may be swayed by the promise of money rather than a safe workplace?

#BringBackMasks #ContinuousMasking #WearARespirator #N95
#CovidIsAirborne

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The "COVID is airborne, mask up" to "vax+relax" to "I've got a cold, again" pipeline is real.

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Masked protesters could soon face arrest, says Home Office

https://www.theguardian.com/uk-news/2024/feb/08/masked-protesters-could-soon-face-arrest-says-home-office

> Protesters who wear masks could face arrest, up to a month in jail and a £1,000 fine under proposed measures

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"it can't possibly cause harm, it's such a small amount! 🤪"

https://phys.org/news/2024-02-pesticide-exposure-affect-fish-generations.html

> Fish exposed to some pesticides at extremely low concentrations for a brief period of time can demonstrate lasting behavioral changes, with the impact extending to offspring that were never exposed firsthand, a recent study found.

trendless, (edited ) to novid
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It's absolutely true that we're not in the same place as in 2020 — back then, most people actually tried not to get/give SARS-CoV-2. Case counts and community transmission were lower, too.

@novid

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> transplanting the gut microbes of people with Alzheimer’s disease into healthy rats causes the animals to develop symptoms of the disease.

> human patients were found to have higher levels of inflammation-promoting bacteria within their fecal samples, which correlated with their degree of cognitive impairment.

> “The memory tests we investigated rely on the growth of new nerve cells in the hippocampus region of the brain. We saw that animals with gut bacteria from people with Alzheimer’s produced fewer new nerve cells and had impaired memory,”

> the team corroborated their findings in human cell cultures, showing that serum from patients with Alzheimer’s disease impaired the growth and functioning of these cells.

https://www.iflscience.com/alzheimers-disease-memory-decline-transferred-to-healthy-young-brains-in-world-first-71211

Study: Microbiota from Alzheimer’s patients induce deficits in cognition and hippocampal neurogenesis (pub. 2023-10-18) ⤵️
https://academic.oup.com/brain/advance-article/doi/10.1093/brain/awad303/7308687?login=false

trendless, to novid
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> By both Ct value and antigen concentration measurements, median viral loads rose from the day of symptom onset and peaked on the fourth/fifth day. Ag RDT sensitivity estimates were 30.0-60.0% on the first day, 59.2-74.8% on the third day, and 80.0-93.3% on the fourth day of symptoms.

> In 74 influenza A PCR-positive individuals (55.4% women; median 35.0y), median influenza viral loads peaked on the second day of symptoms.

> In a highly immune adult population, median SARS-CoV-2 viral loads peaked around the fourth day of symptoms. Influenza A viral loads peaked soon after symptom onset. These findings have implications for ongoing use of Ag RDTs for COVID-19 and influenza.

https://academic.oup.com/cid/advance-article/doi/10.1093/cid/ciad582/7285011

@novid

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“For the first time, we can show that mitochondria, the vital energy producers within brain cells, particularly neurons, undergo damage, leading to disruptions in mitochondrial DNA. This initiates and spreads the disease like a wildfire through the brain… Our findings establish that the spread of the damaged genetic material, the mitochondrial DNA, causes the symptoms reminiscent of Parkinson's disease and its progression to dementia.”

Mitochondrial damage, you say? Are there any highly-transmissible, airborne viruses that cause such a thing? Surely we would do everything to stop them from ripping through the population over and over 🤔

https://medicalxpress.com/news/2023-10-mitochondrial-dna-triggers-parkinson-disease-like.html

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Just subscribed to my first kbin 'magazine' (equivalent to a subreddit) from my Mastodon account -- as easy as copying the link to said magazine, pasting it into the search/explore section, then clicking to follow like it's any other fediverse account

This is the link I copy/pasted 👇
https://kbin.social/m/RedditMigration

More info on the RedditMigration magazine on kbin.social: https://indieweb.social/@tchambers/110601681333124832

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Airflow dynamics scrub classroom air

> research demonstrates that an under-floor air distribution concept combined with a ceiling-distributed exhaust system, which generates local and vertically stretched airflow patterns, can significantly reduce airborne pathogens in classrooms by up to 85 per cent

https://www.sciencedaily.com/releases/2024/03/240306203120.htm

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